Manny Pacquiao's pre-fight words of support to Conor McGregor backfired after the Irishman was knocked out in the second round of his clash with Dustin Poirier at UFC 257.
McGregor was returning to the cage for the first time in a year and was strongly fancied to overcome his American opponent.
But he suffered a brutal KO by Poirier to ensure his comeback would ultimately be an unsuccessful one.
McGregor has recently been in talks with boxing legend Pacquiao over a potential lucrative bout in the ring in the near future.
And before his clash with Poirier the 42-year-old Filipino tweeted: "Good luck tonight Conor! Let's make 2021 the best year ever for fight fans."
But after the shock result Pacquiao went on to congratulate Poirier for his stunning victory afterwards, saying: "Beautiful thing about the fight game, anything can happen! Congrats to @DustinPoirier Huge win."
It remains to be seen what the outcome of the encounter in Abu Dhabi means for McGregor's chances of taking on Pacquiao.
But the Irishman was gracious in defeat, saying: "Dustin is some fighter. I have to dust it off and come back and that’s what I’ll do.
"I'll take my licks. I’m gutted… I put the work in. I’m proud of my work."
Speaking earlier this week about Pacquiao, McGregor appeared confident that something would be finalised very soon.
He told Sportsnet : "It's almost a certainty.
"I'm hearing there's contracts and all coming, you now what I mean? It's that close."
"I haven't spoke, but it should happen in 2021."
Meanwhile YouTuber Jake Paul, who appears desperate to take on McGregor, seemed highly amused by The Notorious' defeat.
In an Instagram video he made reference to a previous lucrative offer he had made, saying: "Hey guys, I got 10,000 dollars for you in cash! Cash baby! You had 50 million dollars!"
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